Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29591678 | 0.78 | MAPK1 (0.52) | MAPK1HPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL2600306 | 0.78 | MAPK1 (0.52) | MAPK1HPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL20812687 | 0.75 | MAPK1 (0.49) | MAPK1HPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL18258621 | 0.74 | IDO1 (0.50) | MAPK1HPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL18258625 | 0.74 | IDO1 (0.50) | MAPK1HPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL29460937 | 0.74 | ALDH1A1 (0.46) | MAPK1HPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL13946119 | 0.74 | LMNA (0.42) | MAPK1HPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL5558970 | 0.73 | HPGD (0.51) | MAPK1HPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL11157197 | 0.71 | MAPK1 (0.45) | MAPK1HPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL20877672 | 0.71 | MAPK1 (0.41) | MAPK1HPGDTSHRUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056497-A | Indolone and relevant derivative with neuroprotective | PFIZER (US) | 1991-11-27 | — | — | CN | disclosed |