Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29108764 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8714650 | 0.98 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL29117803 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28059258 | 0.85 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL17268281 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL29117849 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL15913551 | 0.82 | NPSR1 (0.46) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9436874 | 0.81 | GRIK1 (0.33) | ALDH1A1 | |
| SCHEMBL20530266 | 0.81 | NPSR1 (0.50) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5612684 | 0.81 | NPSR1 (0.50) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935292-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-04-10 | — | — | EP | disclosed |