Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.71 |
| ▸ | MAOB | P27338 | 3/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.71 |
| ▸ | SDHA | P31040 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | CALML3 | P27482 | 1/20 | 0.71 |
| ▸ | F10 | P00742 | 5/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753257 | 1.00 | MAOA (0.71) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL16701350 | 0.91 | MAOA (0.74) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL16701349 | 0.91 | MAOA (0.74) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13034192 | 0.90 | MAOA (0.72) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL12950996 | 0.90 | MAOA (0.72) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3758607 | 0.90 | F10 (0.70) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3328441 | 0.90 | MAOA (0.76) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6097822 | 0.90 | MAOA (0.72) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3328443 | 0.90 | MAOA (0.76) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13054893 | 0.89 | F10 (0.66) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105399737-B | Oxazolidinone compounds and application thereof | 四川好医生药业集团有限公司 | 2018-09-21 | — | — | CN | disclosed |
| EP-2738169-B1 | OXAZOLIDINONE COMPOUNDS AND THEIR USES IN PREPARATION OF ANTIBIOTICS | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO LTD (CN) | 2016-03-23 | — | — | EP | disclosed |
| EP-2738169-B1 | OXAZOLIDINONE COMPOUNDS AND THEIR USES IN PREPARATION OF ANTIBIOTICS | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO LTD (CN) | 2016-03-23 | — | — | EP | disclosed |
| CN-105399737-A | Oxazolidinones compound and application thereof | GOOD DOCTOR PHARMACEUTICAL GROUP CO LTD | 2016-03-16 | — | — | CN | disclosed |
| CN-102827155-B | Oxazolidinone compounds and application of oxazolidinone compound in preparation of antibiotic medicine | UNIV SICHUAN | 2015-03-25 | — | — | CN | disclosed |
| US-8946436-B2 | Oxazolidinone compounds and their uses in preparation of antibiotics | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO., LTD. (CN) | 2015-02-03 | — | — | US | disclosed |
| US-8946436-B2 | Oxazolidinone compounds and their uses in preparation of antibiotics | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO., LTD. (CN) | 2015-02-03 | — | — | US | disclosed |
| EP-2738169-A1 | OXAZOLIDINONE COMPOUNDS AND THEIR USES IN PREPARATION OF ANTIBIOTICS | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO., LTD. (CN) | 2014-06-04 | — | — | EP | disclosed |
| EP-2738169-A1 | OXAZOLIDINONE COMPOUNDS AND THEIR USES IN PREPARATION OF ANTIBIOTICS | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO., LTD. (CN) | 2014-06-04 | — | — | EP | disclosed |
| US-20140142144-A1 | Oxazolidinone Compounds and Their Uses in Preparation of Antibiotics | SI CHUAN UNIVERSITY (CN) | 2014-05-22 | — | — | US | disclosed |
| EP-1200416-A1 | OXAZOLIDINONES AND THEIR USE AS ANTIINFECTIVES | Pharmacia & Upjohn Company (US) | 2002-05-02 | — | — | EP | disclosed |
| EP-0807112-B1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-09-05 | — | — | EP | disclosed |
| WO-2001042242-A1 | ANTIBACTERIAL HETEROBICYCLIC SUBSTITUTED PHENYL OXAZOLIDINONES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-06-14 | — | — | WO | disclosed |
| US-6239152-B1 | Oxazolidinone combinatorial libraries, compositions and methods of preparation | PHARMACIA & UPJOHN COMPANY | 2001-05-29 | — | — | US | disclosed |
| WO-2001009107-A1 | OXAZOLIDINONES AND THEIR USE AS ANTIINFECTIVES | PHARMACIA & UPJOHN COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |
| EP-1049682-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | Versicor, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| US-6124334-A | A BACTERICIDE TREATING INFECTIONS CAUSED BY GRAM-POSITIVE AEROBIC BACTERIA SUCH AS STAPHYLOCOCCUS, STREPTOCOCCUS AND ENTEROCOCCUS AS WELL AS ANAEROBIC ORGANISMS SUCH AS BACTEROIDES AND CLOSTRIDIUM AND MYCOBACTERIDIUM | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1999037630-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | VERSICOR, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
| EP-0807112-A1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023788-A1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA + UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142144-A1 | Oxazolidinone Compounds and Their Uses in Preparation of Antibiotics | OXA1L, ALPI, APC | MAOA 719/4885MAOB 916/4885PTGS1 2482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.