Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19223219 | 0.95 | HPRT1 (0.38) | HPRT1ALDH1A1CYP3A4CYP2C9RIPK1 | |
| SCHEMBL18697843 | 0.91 | CYP3A4 (0.33) | CYP3A4CYP2C9RIPK1 | |
| SCHEMBL18697730 | 0.91 | CYP3A4 (0.33) | CYP3A4CYP2C9RIPK1POLRMT | |
| SCHEMBL881479 | 0.90 | TMPRSS2 (0.36) | HPRT1ALDH1A1CYP3A4CYP2C9RIPK1 | |
| SCHEMBL18697704 | 0.89 | MAPT (0.40) | — | |
| SCHEMBL20078641 | 0.89 | RIPK1 (0.33) | HPRT1ALDH1A1CYP3A4CYP2C9RIPK1 | |
| SCHEMBL20882145 | 0.89 | HPRT1 (0.33) | HPRT1ALDH1A1CYP3A4CYP2C9POLRMT | |
| SCHEMBL24975950 | 0.88 | CYP3A4 (0.39) | HPRT1CYP3A4CYP2C9RIPK1 | |
| SCHEMBL18636394 | 0.88 | CYP3A4 (0.39) | HPRT1CYP3A4CYP2C9RIPK1 | |
| SCHEMBL22342703 | 0.87 | TMPRSS2 (0.41) | HPRT1ALDH1A1CYP3A4CYP2C9RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150608-B1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-04-10 | — | — | EP | disclosed |