SCHEMBL20885488

SCHEMBL20885488

CC(=O)/C=C(\N)C(C)(C)F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24899669 0.79 LMNA (0.37) LMNAALOX15BLMPMP22
SCHEMBL22337471 0.77
SCHEMBL21590037 0.75
SCHEMBL8921055 0.72 MAPT (0.38) LMNAALOX15BLMPMP22
SCHEMBL8921049 0.72 MAPT (0.38) LMNAALOX15BLMPMP22
SCHEMBL22706314 0.69
SCHEMBL622355 0.68
SCHEMBL21974231 0.67 LMNA (0.30) LMNAALOX15BLMPMP22
SCHEMBL9394334 0.67 MAPT (0.40) LMNAALOX15BLMPMP22
SCHEMBL9394330 0.67 MAPT (0.40) LMNAALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019070043-A1 HETEROCYCLIC COMPOUND 武田薬品工業株式会社 2019-04-11 WO disclosed