⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435447 | 0.85 | — | — | |
| SCHEMBL29253076 | 0.81 | — | — | |
| SCHEMBL13792298 | 0.81 | — | — | |
| SCHEMBL19042194 | 0.79 | — | — | |
| SCHEMBL14738364 | 0.78 | — | — | |
| Trifluoroacetamide SCHEMBL7739632 | 0.77 | — | — | |
| Trifluoroacetamide SCHEMBL27598858 | 0.77 | — | — | |
| SCHEMBL9722984 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL29291939 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL15128371 | 0.76 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115838339-B | Heptafluoroisobutyronitrile preparation method and heptafluoroisobutyronitrile | 三明市海斯福化工有限责任公司 | 2024-10-01 | — | — | CN | claimed |
| CN-118056812-A | Continuous preparation method of perfluoroisobutyronitrile | 浙江省化工研究院有限公司 | 2024-05-21 | — | — | CN | claimed |
| CN-115838339-A | Preparation method of heptafluoroisobutyronitrile and heptafluoroisobutyronitrile | 三明市海斯福化工有限责任公司 | 2023-03-24 | — | — | CN | claimed |
| CN-115819277-A | Preparation method of perfluoroisobutyronitrile | 浙江诺亚氟化工有限公司 | 2023-03-21 | — | — | CN | claimed |
| EP-2603496-A1 | 1,4,5,6-TETRAHYDRO-PYRIMIDIN-2-YLAMINE COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-06-19 | — | — | EP | claimed |
| WO-2012019966-A1 | 1,4,5,6-TETRAHYDRO-PYRIMIDIN-2-YLAMINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-02-16 | — | — | WO | claimed |
| WO-2025262036-A1 | METHOD OF MANUFACTURING A PHARMACEUTICAL COMPOSITION | RNASSIST LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| EP-4653438-A1 | MACROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2025-11-26 | — | — | EP | disclosed |
| CN-119080638-A | Perfluoro-iso-benzene preparation method of butyronitrile | 江苏安靠智电股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-119039177-A | Method and device for preparing insulating gas perfluoroalkyl nitrile | 国网(西安)环保技术中心有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-115838339-B | Heptafluoroisobutyronitrile preparation method and heptafluoroisobutyronitrile | 三明市海斯福化工有限责任公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-115838339-B | Heptafluoroisobutyronitrile preparation method and heptafluoroisobutyronitrile | 三明市海斯福化工有限责任公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-115819277-B | Perfluoro-iso-benzene preparation method of butyronitrile | 浙江诺亚氟化工有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-1158315-C | Process for producing ethylene/olefin interpolymers | 伊斯曼化学公司 | 2004-07-21 | — | — | CN | disclosed |
| CN-1144821-C | Procatalysts comprising bidentate ligands, catalyst systems, and use in olefin polymerization | 伊斯曼化学公司 | 2004-04-07 | — | — | CN | disclosed |
| CN-1416440-A | Procatalysts catalyst systems, and use in olefin polymerization | EASTMAN CHEM CO (US) | 2003-05-07 | — | — | CN | disclosed |
| CN-1416439-A | Procatalysts including bidentate ligands, catalyst systems and their use in olefin polymerization | EASTMAN CHEM CO (US) | 2003-05-07 | — | — | CN | disclosed |
| CN-1394212-A | Procatalysts comprising bidentate ligands, catalyst systems, and use in olefin polymerization | EASTMAN CHEM CO (US) | 2003-01-29 | — | — | CN | disclosed |
| CN-1367800-A | Process for producing ethylene/olefin interpolymers | EASTMAN CHEM CO (US) | 2002-09-04 | — | — | CN | disclosed |
| CN-1367798-A | Process for producing ethylene/olefin interpolymers | EASTMAN CHEM CO (US) | 2002-09-04 | — | — | CN | disclosed |