Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 5/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.38 |
| ▸ | FURIN | P09958 | 2/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17722946 | 0.92 | FAP (0.45) | FAPSIRT2SIRT1SIRT3FURIN | |
| SCHEMBL17815311 | 0.92 | FAP (0.45) | FAPSIRT2SIRT1SIRT3FURIN | |
| SCHEMBL20935053 | 0.92 | FAP (0.45) | FAPSIRT2SIRT1SIRT3FURIN | |
| SCHEMBL21998545 | 0.92 | FAP (0.45) | FAPSIRT2SIRT1SIRT3FURIN | |
| SCHEMBL21861811 | 0.92 | FAP (0.45) | FAPSIRT2SIRT1SIRT3FURIN | |
| SCHEMBL22314405 | 0.92 | FAP (0.45) | FAPSIRT2SIRT1SIRT3FURIN | |
| SCHEMBL21912925 | 0.92 | FAP (0.45) | FAPSIRT2SIRT1SIRT3FURIN | |
| SCHEMBL22643670 | 0.92 | FAP (0.45) | FAPSIRT2SIRT1SIRT3FURIN | |
| SCHEMBL19704788 | 0.92 | FAP (0.45) | FAPSIRT2SIRT1SIRT3FURIN | |
| SCHEMBL20889012 | 0.92 | FAP (0.43) | FAPSIRT2SIRT1SIRT3MAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11045480-B2 | Anti-huLRRC15 antibody drug conjugates and methods for their use | ABBVIE INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-20190105328-A1 | ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE | ABBVIE INC. | 2019-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11045480-B2 | Anti-huLRRC15 antibody drug conjugates and methods for their use | LRRC59, LRRC47, HACD3 | FAP 4569/4885SIRT2 4097/4885SIRT1 4465/4885 |
| US-20190105328-A1 | ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE | LRRC59, LRRC47, HACD3 | FAP 4569/4885SIRT2 4097/4885SIRT1 4465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.