Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24632763 | 0.95 | LMNA (0.36) | LMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL22641300 | 0.95 | LMNA (0.36) | LMNAALDH1A1CYP3A4TSHRKMT2A | |
| SCHEMBL24044261 | 0.85 | LMNA (0.33) | LMNAKMT2APAX8 | |
| SCHEMBL19775199 | 0.84 | TSHR (0.31) | TSHR | |
| SCHEMBL22403020 | 0.83 | LMNA (0.32) | LMNA | |
| SCHEMBL14218247 | 0.83 | — | — | |
| SCHEMBL10397619 | 0.81 | EPHX1 (0.41) | LMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL24872407 | 0.81 | LMNA (0.31) | LMNA | |
| SCHEMBL26442744 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRKMT2A | |
| SCHEMBL6271209 | 0.80 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019069270-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-11 | — | — | WO | disclosed |