Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19682585 | 1.00 | HTR2B (0.43) | HTR2BPOLBSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19682584 | 0.83 | NPC1 (0.46) | HTR2BSLC1A3SLC1A2SLC1A1SRD5A2 | |
| SCHEMBL20889365 | 0.83 | NPC1 (0.46) | HTR2BSLC1A3SLC1A2SLC1A1SRD5A2 | |
| SCHEMBL26461857 | 0.76 | HTR2B (0.44) | HTR2BPOLBSRD5A2CHRM2CHRM1 | |
| SCHEMBL8160473 | 0.75 | MAOA (0.42) | HTR2BPOLBCHRM2CHRM1RRM1 | |
| Threonine SCHEMBL29172478 | 0.73 | MEN1 (0.50) | HTR2BPOLBSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL20889301 | 0.72 | CD274 (0.42) | SLC1A3SLC1A2SLC1A1CYP1A2HTR2C | |
| SCHEMBL19682592 | 0.72 | CD274 (0.42) | SLC1A3SLC1A2SLC1A1CYP1A2HTR2C | |
| SCHEMBL19682354 | 0.72 | CYP1A2 (0.41) | HTR2BPOLBCHRM2CHRM1RRM1 | |
| SCHEMBL22310126 | 0.72 | HTR2B (0.43) | HTR2BPOLBSRD5A2MAOACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3718545-A1 | ANTITUMOR AGENT | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-10-07 | — | — | EP | disclosed |
| EP-3466934-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2019-04-10 | — | — | EP | disclosed |