SCHEMBL19682584

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20889365	1.00	NPC1 (0.46)	NPC1RAB9AHTR2BHTR7PNMT
	SCHEMBL21443923	0.86	NPC1 (0.48)	NPC1RAB9AHTR2BHTR7PNMT
	SCHEMBL20889261	0.83	HTR2B (0.43)	NPC1RAB9AHTR2BSLC1A2SLC1A3
	SCHEMBL19682585	0.83	HTR2B (0.43)	NPC1RAB9AHTR2BSLC1A2SLC1A3
	SCHEMBL8197052	0.82	HTR7 (0.47)	NPC1RAB9AHTR2BHTR7PNMT
	SCHEMBL9420910	0.82	NPC1 (0.50)	NPC1RAB9AHTR2BHTR7PNMT
	SCHEMBL21046174	0.82	HTR2B (0.49)	NPC1RAB9AHTR2BHTR7PNMT
	SCHEMBL19682751	0.77	RXRA (0.40)	CHRM2CHRM1RRM1RRM2B
	SCHEMBL19682589	0.77	BCL2L1 (0.41)	CHRM2CHRM1RRM1RRM2B
	SCHEMBL20889215	0.77	BCL2L1 (0.41)	CHRM2CHRM1RRM1RRM2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.