Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.38 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19682371 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1RRM1RRM2BDRD2 | |
| SCHEMBL19682361 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1RRM1RRM2BDRD2 | |
| SCHEMBL20889394 | 0.78 | CHRM2 (0.34) | CHRM2CHRM1RRM1RRM2BDPP4 | |
| SCHEMBL19682374 | 0.78 | CHRM2 (0.34) | CHRM2CHRM1RRM1RRM2BDPP4 | |
| SCHEMBL20889375 | 0.75 | ALOX5 (0.33) | DRD2DPP4DPP7 | |
| SCHEMBL22507751 | 0.75 | ALOX5 (0.33) | DRD2DPP4DPP7 | |
| SCHEMBL19682598 | 0.75 | ALOX5 (0.33) | DRD2DPP4DPP7 | |
| SCHEMBL19682600 | 0.75 | ALOX5 (0.33) | DRD2DPP4DPP7 | |
| SCHEMBL19682589 | 0.73 | BCL2L1 (0.41) | CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL20889377 | 0.73 | RXRA (0.40) | CHRM2CHRM1RRM1RRM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3718545-A1 | ANTITUMOR AGENT | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-10-07 | — | — | EP | disclosed |
| EP-3466934-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2019-04-10 | — | — | EP | disclosed |