Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.34 |
| ▸ | RRM1 | P23921 | 7/20 | 0.34 |
| ▸ | RRM2B | Q7LG56 | 7/20 | 0.34 |
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | RXRG | P48443 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889358 | 1.00 | CHRM2 (0.34) | CHRM2CHRM1RRM1RRM2BRXRA | |
| SCHEMBL22507756 | 1.00 | CHRM2 (0.34) | CHRM2CHRM1RRM1RRM2BRXRA | |
| SCHEMBL20889416 | 0.98 | CHRM2 (0.35) | CHRM2CHRM1RRM1RRM2BRXRA | |
| SCHEMBL22507895 | 0.82 | CHRM2 (0.33) | CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL19682751 | 0.80 | RXRA (0.40) | CHRM2CHRM1RRM1RRM2BRXRA | |
| SCHEMBL20889377 | 0.80 | RXRA (0.40) | CHRM2CHRM1RRM1RRM2BRXRA | |
| SCHEMBL20889250 | 0.78 | NLRP3 (0.32) | CHRM2CHRM1RRM1RRM2BALDH1A1 | |
| SCHEMBL19682589 | 0.78 | BCL2L1 (0.41) | CHRM2CHRM1RRM1RRM2BRXRA | |
| SCHEMBL20889215 | 0.78 | BCL2L1 (0.41) | CHRM2CHRM1RRM1RRM2BRXRA | |
| SCHEMBL19682588 | 0.78 | BCL2L1 (0.41) | CHRM2CHRM1RRM1RRM2BRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466934-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2019-04-10 | — | — | EP | disclosed |