Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12933729 | 0.91 | AHR (0.60) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL25872280 | 0.86 | GAA (0.62) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL31518623 | 0.77 | KMT2A (0.54) | AHRKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL19831074 | 0.77 | KMT2A (0.71) | AHRKMT2AMEN1RAB9AMAPT | |
| SCHEMBL23367868 | 0.76 | GAA (0.60) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL21652259 | 0.75 | GAA (0.58) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL23367870 | 0.74 | GAA (0.57) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL19831068 | 0.74 | KMT2A (0.55) | AHRKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL9674877 | 0.74 | MEN1 (0.54) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL2310087 | 0.73 | MEN1 (0.51) | AHRKMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318959-A1 | Compounds that Inhibit Hiv Particle Formation | UNIVERSITY OF VIRGINIA | 2008-12-25 | — | — | US | claimed |
| WO-2005076861-A2 | COMPOUNDS THAT INHIBIT HIV PARTICLE FORMATION | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2005-08-25 | — | — | WO | claimed |
| US-20110152301-A1 | Compounds that Inhibit HIV Particle Formation | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-06-23 | — | — | US | disclosed |
| US-7875604-B2 | using 3-amino-5-ethyl-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-01-25 | — | — | US | disclosed |
| US-20080318959-A1 | Compounds that Inhibit Hiv Particle Formation | UNIVERSITY OF VIRGINIA | 2008-12-25 | — | — | US | disclosed |
| US-20080318959-A1 | Compounds that Inhibit Hiv Particle Formation | UNIVERSITY OF VIRGINIA | 2008-12-25 | — | — | US | disclosed |
| US-20080318959-A1 | Compounds that Inhibit Hiv Particle Formation | UNIVERSITY OF VIRGINIA | 2008-12-25 | — | — | US | disclosed |
| WO-2005076861-A2 | COMPOUNDS THAT INHIBIT HIV PARTICLE FORMATION | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152301-A1 | Compounds that Inhibit HIV Particle Formation | REV1, VPS51, FLOT1 | AHR 3383/4885KMT2A 4150/4885MEN1 4424/4885 |
| US-20080318959-A1 | Compounds that Inhibit Hiv Particle Formation | REV1, VPS51, FLOT1 | AHR 3383/4885KMT2A 4150/4885MEN1 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.