SCHEMBL2089736

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11660096	0.86	KMT2A (0.53)	KMT2AALDH1A1HPGDKDM4ECYP1A2
	SCHEMBL2089734	0.85	PDK1 (0.50)	PDK1PDK2PDK3PDK4KMT2A
	SCHEMBL5442803	0.85	KMT2A (0.71)	KMT2AALDH1A1HPGDKDM4ECYP1A2
	SCHEMBL3629659	0.85	KMT2A (0.57)	KMT2AALDH1A1HPGDKDM4ESMN1; SMN2
	SCHEMBL11659356	0.83	HPGD (0.64)	KMT2AALDH1A1HPGDKDM4ESMN1; SMN2
	SCHEMBL11686506	0.83	KMT2A (0.50)	KMT2AALDH1A1HPGDKDM4ECYP1A2
	SCHEMBL19805148	0.82	MEN1 (0.68)	KMT2AALDH1A1HPGDKDM4ECYP1A2
	SCHEMBL29992092	0.82	RXFP1 (0.59)	PDK1PDK2PDK3PDK4KMT2A
	SCHEMBL15368377	0.82	RXFP1 (0.59)	PDK1PDK2PDK3PDK4KMT2A
	SCHEMBL505353	0.82	CYP2C19 (0.69)	PDK1PDK2PDK3PDK4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.