Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 7/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20897936 | 0.98 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3HTR3AKCNH2 | |
| SCHEMBL25145660 | 0.80 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HTR3AKCNH2 | |
| SCHEMBL28291346 | 0.76 | MEN1 (0.33) | CHRM2 | |
| SCHEMBL20897972 | 0.76 | MGLL (0.45) | KDM1A | |
| SCHEMBL5202491 | 0.75 | GBA1 (0.53) | SLC6A4SLC6A2SLC6A3GBA1CHRM1 | |
| Hydrochloric Acid SCHEMBL7404020 | 0.74 | GBA1 (0.52) | SLC6A4SLC6A2SLC6A3GBA1CHRM1 | |
| SCHEMBL22265924 | 0.71 | GBA1 (0.45) | SLC6A4SLC6A2SLC6A3HTR3AKCNH2 | |
| SCHEMBL25145973 | 0.71 | CACNA1H (0.45) | SLC6A4SLC6A2SLC6A3HTR3AKCNH2 | |
| SCHEMBL3145121 | 0.70 | GBA1 (0.61) | SLC6A4SLC6A2SLC6A3HTR3AKCNH2 | |
| Trifluoroacetic Acid SCHEMBL21723049 | 0.69 | CACNA1H (0.43) | SLC6A4SLC6A2SLC6A3GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019072978-A1 | MITOCHONDRIAL INHIBITORS FOR THE TREATMENT OF PROLIFERATION DISORDERS | Basilea Pharmaceutica International AG (CH) | 2019-04-18 | — | — | WO | disclosed |