Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 3/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20971746 | 0.81 | GPR119 (0.50) | — | |
| SCHEMBL20897979 | 0.79 | BTK (0.43) | CYP2C9CYP2C19MAPK14BTK | |
| SCHEMBL21722888 | 0.79 | CYP2C9 (0.42) | CYP2C9CYP2C19MAPK14BTK | |
| SCHEMBL20971824 | 0.78 | FAAH (0.37) | SCD | |
| SCHEMBL28291346 | 0.78 | MEN1 (0.33) | MGLLMEN1KMT2ACCR3BTK | |
| SCHEMBL23365148 | 0.77 | MGLL (0.47) | MGLLCYP2C9CYP2C19MAPK14MEN1 | |
| SCHEMBL20897935 | 0.76 | SLC6A4 (0.42) | KDM1A | |
| SCHEMBL6397917 | 0.76 | MGLL (0.66) | MGLLCCR3 | |
| Hydrochloric Acid SCHEMBL20897936 | 0.75 | SLC6A4 (0.41) | KDM1A | |
| SCHEMBL20897951 | 0.74 | L3MBTL1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019072978-A1 | MITOCHONDRIAL INHIBITORS FOR THE TREATMENT OF PROLIFERATION DISORDERS | Basilea Pharmaceutica International AG (CH) | 2019-04-18 | — | — | WO | disclosed |