Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.61 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.61 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | GPR183 | P32249 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | CCNC | P24863 | 1/20 | 0.59 |
| ▸ | CDK8 | P49336 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL27980517 | 0.98 | HPGD (0.71) | HPGDSIGMAR1POLBCHRNB2CHRNB4 | |
| SCHEMBL20631562 | 0.88 | HPGD (0.86) | HPGDPOLBGAAGPR183ALDH1A1 | |
| SCHEMBL8256141 | 0.86 | SIGMAR1 (0.66) | HPGDSIGMAR1POLBCHRNB2CHRNB4 | |
| SCHEMBL8358137 | 0.86 | SIGMAR1 (0.81) | HPGDSIGMAR1ALDH1A1L3MBTL1 | |
| SCHEMBL2534411 | 0.84 | HPGD (1.00) | HPGDPOLBGAAALDH1A1L3MBTL1 | |
| SCHEMBL8660373 | 0.83 | SIGMAR1 (0.62) | HPGDSIGMAR1GPR183ALDH1A1CCNC | |
| SCHEMBL16026516 | 0.83 | ALDH1A1 (0.61) | SIGMAR1GAAALDH1A1TSHR | |
| SCHEMBL2535536 | 0.83 | HPGD (0.96) | HPGDPOLBGAAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9621122 | 0.82 | ALDH1A1 (0.60) | HPGDSIGMAR1GAAALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL17559360 | 0.82 | HPGD (0.63) | HPGDSIGMAR1GPR183ALDH1A1CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | claimed |
| EP-2779217-A2 | Chemical mechanical planarization for tungsten-containing substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-17 | — | — | EP | claimed |
| CN-101412708-A | Duloxetine derivative and preparation thereof | UNIV HEBEI TECHNOLOGY (CN) | 2009-04-22 | — | — | CN | claimed |
| CN-117820287-B | Magnolol derivative, and preparation method and application thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-119823089-A | N-phenyl-2-azacyclic acetamide derivative, and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2025-04-15 | — | — | CN | disclosed |
| CN-119143715-B | Diaryl methylpiperazine compound and preparation method, pharmaceutical composition and application thereof | 天津匠新致成科技有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119143715-A | Diaryl methylpiperazine compound and preparation method, pharmaceutical composition and application thereof | 天津匠新致成科技有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-117820287-A | Magnolol derivative, and preparation method and application thereof | 中国药科大学 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023066190-A1 | COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-04-27 | — | — | WO | disclosed |
| CN-112390751-B | Toll-like receptor-7 small molecule inhibitor and preparation method thereof | 清华大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-112390751-A | Toll-like receptor-7 small molecule inhibitor and preparation method thereof | 清华大学 | 2021-02-23 | — | — | CN | disclosed |
| US-7157469-B2 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS (US) | 2007-01-02 | — | — | US | disclosed |
| WO-2005056524-A2 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 2005-06-23 | — | — | WO | disclosed |
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |
| EP-0242957-B1 | 1-SUBSTITUTED ALKYL-1, 2-DIHYDRO-2-PYRAZINONE DERIVATIVES | TOYO JOZO KABUSHIKI KAISHA (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4877875-A | ANTIAGGLOMERANTS, VASODILATORS | TOYO JOZO KABUSHIKI KAISHA (JP) | 1989-10-31 | — | — | US | disclosed |
| US-4837319-A | VASODILATORS, ANTICOAGULANTS | TOYO JOZO KABUSHIKI KAISHA (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0242957-A1 | 1-Substituted Alkyl-1, 2-Dihydro-2-Pyrazinone derivatives | TOYO JOZO KABUSHIKI KAISHA (JP) | 1987-10-28 | — | — | EP | disclosed |
| US-4610984-A | CEREBRAL INSUFFICIENCY | CASSELLA AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
| EP-0123977-A1 | Substituted piperazin-1-yl-acetic-acid amides, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1984-11-07 | — | — | EP | disclosed |