Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733588 | 0.74 | HTR2A (0.36) | HTR2AHTR2CHTR2BALDH1A1MAPT | |
| SCHEMBL9449722 | 0.74 | MAPT (0.38) | HTR2AHTR2CHTR2BALDH1A1MAPT | |
| SCHEMBL10400093 | 0.70 | SRC (0.47) | ALDH1A1MAPTPNMTCYP3A4ALOX15 | |
| SCHEMBL20898871 | 0.68 | HTR2A (0.54) | HTR2AHTR2CHTR2BALDH1A1MAPT | |
| SCHEMBL20898566 | 0.66 | HTR2A (0.38) | HTR2AHTR2CHTR2BALDH1A1MAPT | |
| SCHEMBL20898072 | 0.65 | ALDH1A1 (0.38) | HTR2AHTR2CHTR2BALDH1A1MAPT | |
| SCHEMBL31731530 | 0.65 | MAPT (0.44) | HTR2AHTR2CHTR2BALDH1A1MAPT | |
| SCHEMBL5126377 | 0.65 | HTR2A (0.33) | HTR2AHTR2CHTR2BALDH1A1MAPT | |
| SCHEMBL34463424 | 0.64 | CA12 (0.36) | ALDH1A1MAPT | |
| SCHEMBL2913056 | 0.64 | TDP1 (0.38) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019072978-A1 | MITOCHONDRIAL INHIBITORS FOR THE TREATMENT OF PROLIFERATION DISORDERS | Basilea Pharmaceutica International AG (CH) | 2019-04-18 | — | — | WO | disclosed |