Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609002 | 0.83 | HSD11B1 (0.56) | HSD11B1HSD17B1HSD17B2F2SLC40A1 | |
| SCHEMBL6610280 | 0.78 | PFKFB3 (0.40) | SLC40A1POLBMAPTPFKFB3 | |
| SCHEMBL6613632 | 0.77 | SLC40A1 (0.49) | HSD11B1HSD17B1HSD17B2F2SLC40A1 | |
| SCHEMBL6612070 | 0.76 | HSD11B1 (0.40) | HSD11B1HSD17B1HSD17B2SLC40A1POLB | |
| SCHEMBL6696911 | 0.76 | HSD11B1 (0.66) | HSD11B1HSD17B1HSD17B2F2SLC40A1 | |
| SCHEMBL6612821 | 0.72 | HSD11B1 (0.52) | HSD11B1HSD17B1HSD17B2F2SLC40A1 | |
| SCHEMBL6614777 | 0.72 | PFKFB3 (0.35) | HSD11B1HSD17B1HSD17B2SLC40A1POLB | |
| SCHEMBL6610456 | 0.72 | HSD11B1 (0.55) | HSD11B1HSD17B1HSD17B2F2SLC40A1 | |
| SCHEMBL6693049 | 0.71 | SLC40A1 (0.43) | HSD11B1SLC40A1 | |
| SCHEMBL6616669 | 0.71 | PFKFB3 (0.36) | HSD11B1SLC40A1POLBMAPTPFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019075394-A1 | COMPOUNDS FOR TREATMENT OF EMOTIONAL/PSYCHOLOGICAL SYMPTOMS IN FRAGILE X SYNDROME | VANDERKLISH PETER (US) | 2019-04-18 | — | — | WO | disclosed |