Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20901119 | 0.97 | KMT2A (0.38) | MEN1KMT2ALMNABRAFALDH1A1 | |
| SCHEMBL20050791 | 0.94 | MEN1 (0.40) | MEN1KMT2ALMNABRAFALDH1A1 | |
| SCHEMBL24281334 | 0.94 | BRAF (0.39) | MEN1KMT2ALMNABRAFALDH1A1 | |
| SCHEMBL20050385 | 0.94 | BRAF (0.39) | MEN1KMT2ALMNABRAFALDH1A1 | |
| SCHEMBL20901147 | 0.93 | MEN1 (0.39) | MEN1KMT2ALMNABRAFALDH1A1 | |
| SCHEMBL20051370 | 0.93 | KMT2A (0.40) | MEN1KMT2ALMNABRAFALDH1A1 | |
| SCHEMBL24281831 | 0.93 | KMT2A (0.40) | MEN1KMT2ALMNABRAFALDH1A1 | |
| SCHEMBL20050410 | 0.92 | MEN1 (0.36) | MEN1KMT2ALMNABRAFALDH1A1 | |
| SCHEMBL20901046 | 0.91 | KMT2A (0.38) | MEN1KMT2ALMNABRAFALDH1A1 | |
| SCHEMBL20050788 | 0.91 | KMT2A (0.38) | MEN1KMT2ALMNABRAFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971166-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO | Corteva Agriscience LLC (US) | 2022-03-23 | — | — | EP | disclosed |
| US-20210161144-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2021-06-03 | — | — | US | disclosed |
| US-10993440-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes related thereto | DOW AGROSCIENCES LLC (US) | 2021-05-04 | — | — | US | disclosed |
| US-20190166847-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-06-06 | — | — | US | disclosed |
| US-20190150452-A1 | MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-23 | — | — | US | disclosed |
| US-10258045-B2 | Molecules having pesticidal utility and intermediates, compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2019-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190166847-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | MEN1 915/4885KMT2A 2668/4885LMNA 3336/4885 |
| US-10993440-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes related thereto | ACHE, DDT, MLYCD | MEN1 915/4885KMT2A 2668/4885LMNA 3336/4885 |
| US-20210161144-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | MEN1 1180/4885KMT2A 2615/4885LMNA 3364/4885 |
| US-10258045-B2 | Molecules having pesticidal utility and intermediates, compositions and processes related thereto | ACHE, DDT, MLYCD | MEN1 1462/4885KMT2A 3043/4885LMNA 3786/4885 |
| US-20190150452-A1 | MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | MEN1 912/4885KMT2A 2547/4885LMNA 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.