Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1277271 | 0.74 | TRPV1 (0.52) | CCNE1CDK2CDK5NPC1RAB9A | |
| SCHEMBL31370410 | 0.73 | AKR1B1 (0.43) | — | |
| SCHEMBL8701763 | 0.73 | ALDH1A1 (0.54) | SLC1A3LMNAGAAMEN1KMT2A | |
| SCHEMBL9046891 | 0.73 | ALDH1A1 (0.54) | SLC1A3LMNAGAAMEN1KMT2A | |
| SCHEMBL8134776 | 0.73 | ALDH1A1 (0.54) | SLC1A3LMNAGAAMEN1KMT2A | |
| SCHEMBL6190209 | 0.72 | CSF1R (0.40) | LMNAMEN1KMT2ACYP1A2WNT1 | |
| SCHEMBL8131978 | 0.72 | SLC1A3 (0.47) | SLC1A3CCNE1CDK2CDK5NPC1 | |
| SCHEMBL1849668 | 0.72 | SLC1A3 (0.56) | SLC1A3CCNE1CDK2CDK5NPC1 | |
| SCHEMBL21460379 | 0.72 | KDM4E (0.52) | CCNE1CDK2CDK5RAB9AGAA | |
| SCHEMBL20318831 | 0.72 | KDM4E (0.52) | CCNE1CDK2CDK5RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10259785-B2 | Therapeutic compounds and compositions | EXITHERA PHARMACEUTICALS, INC. (US) | 2019-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10259785-B2 | Therapeutic compounds and compositions | KLK5, KLKB1, KLK2 | SLC1A3 4691/4885CCNE1 3130/4885CDK2 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.