Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20901751 | 0.86 | FFAR1 (0.44) | LMNARAB9ANPC1SRCCASP3 | |
| SCHEMBL19801255 | 0.85 | LMNA (0.52) | LMNARAB9ANPC1SRCCASP3 | |
| SCHEMBL4315897 | 0.83 | KDM4E (0.63) | LMNARAB9ANPC1SRCCASP3 | |
| SCHEMBL4319595 | 0.83 | ATM (0.57) | LMNARAB9ANPC1SRCCASP3 | |
| SCHEMBL3911634 | 0.80 | ATM (0.58) | LMNARAB9ANPC1SRCCASP3 | |
| SCHEMBL20266311 | 0.75 | ATM (0.74) | LMNARAB9ANPC1SRCCASP3 | |
| SCHEMBL22272749 | 0.72 | POLB (0.62) | LMNARAB9ANPC1KDM4EHSD17B10 | |
| SCHEMBL17967149 | 0.71 | FFAR1 (0.48) | LMNASRCALDH1A1CES1MEN1 | |
| SCHEMBL19801239 | 0.71 | FFAR1 (0.44) | LMNARAB9ANPC1SRCCASP3 | |
| SCHEMBL17967116 | 0.70 | FFAR1 (0.52) | RAB9ANPC1SRCCASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3253748-B1 | AUTOTAXIN INHIBITORS | CANCER RESEARCH TECH LTD (GB) | 2019-04-17 | — | — | EP | disclosed |