Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19801239 | 0.86 | FFAR1 (0.44) | FFAR1ENPP2HDAC1HDAC6NPC1 | |
| SCHEMBL20901779 | 0.86 | LMNA (0.52) | NPC1LMNACASP3RAB9ASENP7 | |
| SCHEMBL19793299 | 0.82 | FFAR1 (0.47) | FFAR1ENPP2HDAC1HDAC6NPC1 | |
| SCHEMBL17967710 | 0.81 | FFAR1 (0.44) | FFAR1ENPP2HDAC1HDAC6NPC1 | |
| Hydrochloric Acid SCHEMBL21391937 | 0.80 | FFAR1 (0.43) | FFAR1ENPP2HDAC1HDAC6NPC1 | |
| SCHEMBL17967149 | 0.72 | FFAR1 (0.48) | FFAR1ENPP2LMNASRCMEN1 | |
| SCHEMBL19801255 | 0.71 | LMNA (0.52) | NPC1LMNACASP3RAB9ASENP7 | |
| SCHEMBL17967187 | 0.70 | KDM4E (0.48) | FFAR1ENPP2NPC1LMNARAB9A | |
| SCHEMBL4315897 | 0.69 | KDM4E (0.63) | NPC1GLSLMNACASP3RAB9A | |
| SCHEMBL17967711 | 0.69 | ATM (0.69) | GLSLMNAPOLBHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3253748-B1 | AUTOTAXIN INHIBITORS | CANCER RESEARCH TECH LTD (GB) | 2019-04-17 | — | — | EP | disclosed |