SCHEMBL20902007

SCHEMBL20902007

Cc1cccc(N(N)C(=O)NN)c1COc1ccn(-c2ccc(Cl)cc2)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
NR1H4 Q96RI1 1/20 0.37
SIGMAR1 Q99720 4/20 0.36
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
GAA P10253 2/20 0.35
PKM P14618 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.33
LMNA P02545 2/20 0.33
TRPA1 O75762 1/20 0.32
KCNH2 Q12809 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
UBE2N P61088 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22564091 0.92 NR1H4 (0.38) ALDH1A1NR1H4MAPTKDM4EGAA
SCHEMBL19909882 0.91 NR1H4 (0.33) ALDH1A1CYP1A2CYP3A4NR1H4NPC1
SCHEMBL22564351 0.89 ALDH1A1 (0.36) ALDH1A1NR1H4MAPTPKMLMNA
SCHEMBL19909894 0.89 CTDSP1 (0.42) ALDH1A1CYP1A2CYP3A4NR1H4SIGMAR1
SCHEMBL22564110 0.89 ALDH1A1 (0.41) ALDH1A1CYP1A2CYP3A4NR1H4SIGMAR1
SCHEMBL22563766 0.89 CYP1A2 (0.44) ALDH1A1CYP1A2CYP3A4NR1H4SIGMAR1
SCHEMBL22564003 0.88 ALDH1A1 (0.39) ALDH1A1CYP1A2CYP3A4NR1H4SIGMAR1
SCHEMBL22563758 0.88 UBE2N (0.35) ALDH1A1NR1H4MAPTNPC1RAB9A
SCHEMBL22563988 0.88 ALDH1A1 (0.39) ALDH1A1CYP1A2CYP3A4NR1H4SIGMAR1
SCHEMBL22564161 0.87 NR1H4 (0.37) ALDH1A1CYP3A4NR1H4SIGMAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
EP-3025586-B1 PLANT DISEASE CONTROL COMPOSITION AND ITS USE SUMITOMO CHEMICAL CO (JP) 2019-04-17 EP disclosed