SCHEMBL19909882

SCHEMBL19909882

Cc1cccc(N(N)C(=O)NN)c1COc1ccn(-c2ccc(Br)cc2)n1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.33
PTGER1 P34995 1/20 0.31
ALDH1A1 P00352 3/20 0.31
LMNA P02545 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
RAB9A P51151 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
HTT P42858 1/20 0.30
NFKB1 P19838 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22564091 0.92 NR1H4 (0.38) NR1H4ALDH1A1HTT
SCHEMBL22564154 0.91 NR1H4 (0.37) NR1H4PTGER1ALDH1A1LMNARAB9A
SCHEMBL20902007 0.91 ALDH1A1 (0.41) NR1H4ALDH1A1LMNACYP1A2CYP3A4
SCHEMBL22563771 0.90 NR1H4 (0.33) NR1H4ALDH1A1LMNACYP1A2CYP3A4
SCHEMBL22564351 0.89 ALDH1A1 (0.36) NR1H4ALDH1A1LMNASMN1; SMN2
SCHEMBL22563767 0.89 NR1H4 (0.38) NR1H4ALDH1A1CYP1A2CYP3A4CA12
SCHEMBL20844975 0.88 MCHR1 (0.33) NR1H4PTGER1RAB9ANPC1TP53
SCHEMBL22563758 0.88 UBE2N (0.35) NR1H4ALDH1A1RAB9ANPC1
SCHEMBL22564385 0.87 ALDH1A1 (0.35) NR1H4ALDH1A1CYP1A2CYP3A4CA12
SCHEMBL22563775 0.87 ALDH1A1 (0.31) NR1H4ALDH1A1LMNARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3025586-B1 PLANT DISEASE CONTROL COMPOSITION AND ITS USE SUMITOMO CHEMICAL CO (JP) 2019-04-17 EP disclosed
EP-3025585-B1 PLANT DISEASE CONTROL COMPOSITION AND ITS USE SUMITOMO CHEMICAL CO (JP) 2018-02-28 EP disclosed