Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025962 | 0.87 | CA12 (0.62) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL5627215 | 0.78 | GAA (0.56) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL31196721 | 0.78 | GAA (0.56) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL5928677 | 0.78 | KDM4E (0.71) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL12846929 | 0.78 | SMN1; SMN2 (0.47) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL5899451 | 0.78 | ALDH1A1 (0.67) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL31337030 | 0.78 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17881940 | 0.77 | SMN1; SMN2 (0.53) | MAPTPOLBKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL26046942 | 0.76 | RAB9A (0.49) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL14503722 | 0.76 | CA12 (0.49) | NPC1POLBKDM4ESMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2672820-B1 | MANNOSIDE COMPOUNDS AND METHODS OF USE THEREOF | UNIV WASHINGTON (US) | 2019-04-17 | — | — | EP | disclosed |