⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639997 | 0.77 | — | — | |
| SCHEMBL855873 | 0.75 | — | — | |
| SCHEMBL3072164 | 0.75 | — | — | |
| SCHEMBL606580 | 0.75 | — | — | |
| SCHEMBL27834400 | 0.75 | — | — | |
| SCHEMBL7989729 | 0.75 | — | — | |
| SCHEMBL2091057 | 0.75 | — | — | |
| SCHEMBL8241737 | 0.73 | — | — | |
| SCHEMBL27458822 | 0.73 | — | — | |
| SCHEMBL14402594 | 0.72 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755476-B | Method for producing compound | 住友化学株式会社 | 2017-12-05 | — | — | CN | disclosed |
| EP-1756075-B1 | COMPOUND FOR PREPARING THIAZOLE BY AMINOMETHYLATION | SUMITOMO CHEMICAL CO (JP) | 2013-08-07 | — | — | EP | disclosed |
| EP-1866297-B1 | PROCESS FOR PRODUCING AN AMINOMETHYL THIAZOLE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2011-12-28 | — | — | EP | disclosed |
| US-7977490-B2 | Process for producing thiazole compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20110054185-A1 | PROCESS FOR PRODUCING THIAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
| CN-101189217-B | Process for producing an aminomethyl thiazole compound | SUMITOMO CHEMICAL CO | 2011-01-26 | — | — | CN | disclosed |
| CN-1968938-B | Method for preparing thiazole by aminomethylation | SUMITOMO CHEMICAL CO | 2010-05-05 | — | — | CN | disclosed |
| US-7439357-B2 | Process for preparing thiazole by aminomethylation | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-21 | — | — | US | disclosed |
| CN-101189217-A | Process for producing an aminomethyl thiazole compound | SUMITOMO CHEMICAL CO (JP) | 2008-05-28 | — | — | CN | disclosed |
| EP-1866297-A1 | PROCESS FOR PRODUCING AN AMINOMETHYL THIAZOLE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-12-19 | — | — | EP | disclosed |
| US-20070197803-A1 | Process for preparing thiazole by aminomethylation | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-08-23 | — | — | US | disclosed |
| CN-1968938-A | Method for preparing thiazole by aminomethylation | SUMITOMO CHEMICAL CO (JP) | 2007-05-23 | — | — | CN | disclosed |
| EP-1756075-A1 | COMPOUND FOR PREPARING THIAZOLE BY AMINOMETHYLATION | Sumitomo Chemical Company, Limited (JP) | 2007-02-28 | — | — | EP | disclosed |
| WO-2006109811-A1 | PROCESS FOR PRODUCING AN AMINOMETHYL THIAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-19 | — | — | WO | disclosed |
| WO-2005123704-A1 | COMPOUND FOR PREPARING THIAZOLE BY AMINOMETHYLATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-12-29 | — | — | WO | disclosed |