⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229408 | 0.81 | — | — | |
| SCHEMBL1419766 | 0.78 | HDAC1 (0.35) | — | |
| SCHEMBL1639997 | 0.77 | — | — | |
| SCHEMBL7989729 | 0.75 | — | — | |
| SCHEMBL27834400 | 0.75 | — | — | |
| SCHEMBL2090380 | 0.75 | — | — | |
| SCHEMBL855873 | 0.75 | — | — | |
| SCHEMBL2956791 | 0.75 | — | — | |
| SCHEMBL6234352 | 0.75 | — | — | |
| SCHEMBL281998 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483440-A | A kind of preparation method of 2- (the bromo- 1,3- thiazole -5- base of 2-) acetonitrile | SHANGHAI RAISE CHEMICAL TECH CO LTD | 2019-11-22 | — | — | CN | claimed |
| EP-1007517-B1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYLTHIAZOLES | ABBOTT LAB (US) | 2003-10-08 | — | — | EP | claimed |
| EP-1007517-A1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYLTHIAZOLES | Abbott Laboratories (US) | 2000-06-14 | — | — | EP | claimed |
| WO-1999011636-A1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYLTHIAZOLES | ABBOTT LABORATORIES (US) | 1999-03-11 | — | — | WO | claimed |
| US-20260042747-A1 | KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | ALIVEXIS, INC. (JP) | 2026-02-12 | — | — | US | disclosed |
| US-20250340546-A1 | HSD17B13 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2025-11-06 | — | — | US | disclosed |
| EP-4085057-B1 | PYRIDINE AND PYRIMIDINE DERIVATIVES USEFUL AS PQSR INVERSE AGONISTS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-10-08 | — | — | EP | disclosed |
| US-12421222-B2 | Substituted quinazolines as HDAC6 inhibitors | AUGUSTINE THERAPEUTICS (BE) | 2025-09-23 | — | — | US | disclosed |
| US-12410210-B2 | Neuroactive steroids and their methods of use | SAGE THERAPEUTICS, INC. (US) | 2025-09-09 | — | — | US | disclosed |
| EP-4565575-A1 | KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | Alivexis, Inc. (JP) | 2025-06-11 | — | — | EP | disclosed |
| US-20250154194-A1 | NEUROACTIVE STEROIDS AND THEIR METHODS OF USE | SAGE THERAPEUTICS, INC. | 2025-05-15 | — | — | US | disclosed |
| US-20250145604-A1 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2025-05-08 | — | — | US | disclosed |
| WO-2008061795-A2 | N- (METHYL) -1H- PYRAZOL- 3 -AMINE, N- (METHYL) -PYRIDIN-2-AMINE AND N- (METHYL) -THIAZ0L-2-AMINE DERIVATIVES FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID OR AMYLOID-LIKE PROTEINS, LIKE E.G. ALZHEIMER'S | AC IMMUNE SA (CH) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008057336-A2 | HETEROCYCLYL-SUBSTITUTED ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS | MERCK & CO., INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| US-7304087-B2 | 1-acyl-pyrrolidine derivatives for the treatment of viral infections | GLAXO GROUP LIMITED (GB) | 2007-12-04 | — | — | US | disclosed |
| WO-2007002557-A1 | NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060258720-A1 | 1-Acyl-pyrrolidine derivatives for the treatment of viral infections | GLAXO GROUP LIMITED (GB) | 2006-11-16 | — | — | US | disclosed |
| CN-1732165-A | 1-acyl-pyrrolidine derivatives for the treatment of viral infections | GLAXO GROUP LTD (GB) | 2006-02-08 | — | — | CN | disclosed |
| EP-1554274-A1 | 1-ACYL-PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004037818-A1 | 1-ACYL-PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2004-05-06 | — | — | WO | disclosed |