Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19542313 | 0.79 | ALDH1A1 (0.58) | ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT | |
| SCHEMBL6853611 | 0.78 | ALDH1A1 (0.64) | ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT | |
| SCHEMBL224829 | 0.78 | ALDH1A1 (0.64) | ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT | |
| SCHEMBL4956384 | 0.76 | CYP2A6 (0.69) | ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT | |
| SCHEMBL31171 | 0.76 | CYP2A6 (0.69) | ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT | |
| SCHEMBL18726334 | 0.74 | ALDH1A1 (0.58) | ALDH1A1 | |
| SCHEMBL195687 | 0.74 | ALDH1A1 (1.00) | ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT | |
| SCHEMBL14464899 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT | |
| SCHEMBL5878042 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT | |
| Water SCHEMBL29197442 | 0.73 | CYP2A6 (0.65) | ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020073011-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. (US) | 2020-04-09 | — | — | WO | disclosed |
| WO-2019075357-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-04-18 | — | — | WO | disclosed |