SCHEMBL224829

SCHEMBL224829

O=Cc1ccc(SSc2ccc(C=O)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.64
CYP2A6 P11509 4/20 0.50
HSD17B10 Q99714 2/20 0.50
ALDH5A1 P51649 1/20 0.50
ABAT P80404 1/20 0.50
KDM4E B2RXH2 2/20 0.44
TYR P14679 1/20 0.44
CYP2A13 Q16696 1/20 0.44
ALDH1A3 P47895 2/20 0.41
ALDH3A1 P30838 1/20 0.41
EGFR P00533 1/20 0.39
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39
PTGS2 P35354 1/20 0.39
RAB9A P51151 1/20 0.39
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MGLL Q99685 1/20 0.38
STS P08842 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL28323560 0.95 ALDH1A1 (0.58) ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL19888533 0.82 ALDH1A1 (0.76) ALDH1A1CYP2A6KDM4EALDH1A3PTGS2
SCHEMBL6853611 0.82 ALDH1A1 (0.64) ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL31171 0.80 CYP2A6 (0.69) ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL4956384 0.80 CYP2A6 (0.69) ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL5878042 0.78 ALDH1A1 (0.58) ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL20904129 0.78 ALDH1A1 (0.58) ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL14464899 0.78 ALDH1A1 (0.58) ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL195687 0.78 ALDH1A1 (1.00) ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL19542313 0.78 ALDH1A1 (0.58) ALDH1A1CYP2A6HSD17B10ALDH5A1ABAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 646 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115501239-B Bionic drug-loading system for targeting lung cancer drug-resistant tumor and preparation method and application thereof 中国人民解放军陆军特色医学中心 2023-12-12 CN claimed
CN-115449088-B High-pore COF nano-particle, preparation method thereof and application thereof as drug carrier 中国人民解放军陆军特色医学中心 2023-06-16 CN claimed
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
US-10933285-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2021-03-02 US disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
WO-2000038794-A9 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET CO (US) 2001-11-01 WO disclosed
US-20010024982-A1 Thin-layer-covered multilayer golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2001-09-27 US disclosed
US-6291592-B1 HARDNESS, STIFFNESS ACUSHNET COMPANY 2001-09-18 US disclosed
WO-2000038794-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038793-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING ELEMENTAL CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038795-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AROMATIC CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 US disclosed