Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053649 | 0.90 | TSHR (0.52) | TSHRHPGDNPY5RKMT2AMEN1 | |
| SCHEMBL20888587 | 0.82 | LMNA (0.62) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL20904187 | 0.82 | NPSR1 (0.55) | ALDH1A1MAPTNPY5RCA12CA1 | |
| SCHEMBL20904180 | 0.81 | CA12 (0.55) | NPY5RCA12CA1CA2CA5A | |
| SCHEMBL12856883 | 0.77 | NPY5R (0.54) | GAATSHRNPY5RKMT2AMEN1 | |
| SCHEMBL1515926 | 0.77 | LMNA (0.55) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL5966848 | 0.76 | TSHR (0.50) | TSHRNPY5RKMT2AMEN1 | |
| SCHEMBL2625190 | 0.75 | LMNA (0.62) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL20904160 | 0.74 | CA12 (0.55) | NPY5RCA12CA1CA2CA5A | |
| Felbinac SCHEMBL384892 | 0.74 | LMNA (0.95) | ABCC4LMNAGAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200289486-A1 | Enantiomers Of Substituted Thiazoles As Antiviral Compounds | INNOVATIVE MOLECULES GMBH (DE) | 2020-09-17 | — | — | US | disclosed |
| US-20200148652-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | INNOVATIVE MOLECULES GMBH (DE) | 2020-05-14 | — | — | US | disclosed |
| US-10590094-B2 | Aminothiazole derivatives useful as antiviral agents | INNOVATIVE MOLECULES GMBH (DE) | 2020-03-17 | — | — | US | disclosed |
| US-20190112285-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | INNOVATIVE MOLECULES GMBH (DE) | 2019-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148652-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | MAVS, EIF2AK2, SARS1 | ABCC4 2595/4885LMNA 4099/4885GAA 710/4885 |
| US-20190112285-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | MAVS, EIF2AK2, SARS1 | ABCC4 2433/4885LMNA 4100/4885GAA 665/4885 |
| US-20200289486-A1 | Enantiomers Of Substituted Thiazoles As Antiviral Compounds | EIF2AK2, MAVS, ZC3HAV1 | ABCC4 1287/4885LMNA 3312/4885GAA 416/4885 |
| US-10590094-B2 | Aminothiazole derivatives useful as antiviral agents | MAVS, EIF2AK2, SARS1 | ABCC4 2433/4885LMNA 4100/4885GAA 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.