SCHEMBL209046

SCHEMBL209046

O=C1C=CC(=O)N1C1CCCC1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
CYP2C9 P11712 3/20 0.48
CYP2C19 P33261 3/20 0.48
CYP3A4 P08684 1/20 0.48
KMT2A Q03164 1/20 0.48
NPSR1 Q6W5P4 1/20 0.40
POLB P06746 2/20 0.38
LMNA P02545 2/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
HTT P42858 1/20 0.37
CREBBP Q92793 1/20 0.37
HSD17B10 Q99714 1/20 0.37
OPRM1 P35372 1/20 0.37
OPRK1 P41145 1/20 0.37
OPRL1 P41146 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18209593 1.00 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL15492440 0.97 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL25434872 0.97 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL20375020 0.97 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL25118469 0.97 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL24079397 0.97 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL1059882 0.97 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL28719 0.97 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL209153 0.97 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL212326 0.97 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110724154-A Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof 湖北科技学院 2020-01-24 CN claimed
US-9932432-B2 Polymers of maleimide and cycloolefinic monomers as permanent dielectric materials PROMERUS, LLC (US) 2018-04-03 US claimed
US-20160326292-A1 POLYMERS OF MALEIMIDE AND CYCLOOLEFINIC MONOMERS AS PERMANENT DIELECTRIC MATERIALS SUMITOMO BAKELITE CO., LTD. (JP) 2016-11-10 US claimed
EP-1817376-B1 HYBRID THERMOSETTING COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2012-08-22 EP claimed
CN-102120794-A Method for preparing optical fiber preforming rod CHENGDU HENGTONG OPTICAL COMM 2011-07-13 CN claimed
CN-101068879-B Hybrid thermosetting composition 3M INNOVATIVE PROPERTIES CO 2010-10-13 CN claimed
CN-101068879-A Hybrid thermosetting composition 3M INNOVATIVE PROPERTIES CO (US) 2007-11-07 CN claimed
CN-101068839-A Branched polymer 3M INNOVATIVE PROPERTIES CO (US) 2007-11-07 CN claimed
EP-1817376-A1 HYBRID THERMOSETTING COMPOSITION 3M Innovative Properties Company (US) 2007-08-15 EP claimed
EP-1817353-A1 BRANCHED POLYMER 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-08-15 EP claimed
WO-2006060092-A1 HYBRID THERMOSETTING COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-06-08 WO claimed
WO-2006060086-A1 BRANCHED POLYMER 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-06-08 WO claimed
US-20060116492-A1 Branched polymer 3M INNOVATIVE PROPERTIES COMPANY 2006-06-01 US claimed
US-20060116476-A1 Hybrid thermosetting composition 3M INNOVATIVE PROPERTIES COMPANY 2006-06-01 US claimed
CN-1138161-C Preparation of prefabricated optical fiber rod of heat resisting plastics 中国科学院感光化学研究所 2004-02-11 CN claimed
CN-1298109-A Preparation of prefabricated optical fiber rod of heat resisting plastics INST OF PHOTOCHEMISTRY ACADEMI (CN) 2001-06-06 CN claimed
US-5096948-A Maleimide copolymer, hindered amine stabilizer, discoloration inhibition SANKYO COMPANY, LIMITED (JP) 1992-03-17 US claimed
US-4918152-A COPOLYMERIZATION WITH A MALEIMIDE AND POLYFUNCTIONAL MONOMER; SMALL BIREFRINGENCE, HIGH REFRACTIVE INDEX; HIGH SPEED SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-04-17 US claimed
CN-122054878-A Method for manufacturing light-emitting device, negative-type radiation-sensitive composition, cured film, and organic EL device JSR株式会社 2026-05-15 CN disclosed
EP-0295012-A2 Process for the production of formed article of aromatic vinyl resin SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-12-14 EP disclosed