Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095414 | 0.86 | ALDH1A1 (0.42) | LTA4HCA4ALDH1A1HTTKMT2A | |
| SCHEMBL1532097 | 0.84 | TEAD4 (0.42) | LTA4HALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8535180 | 0.83 | LTA4H (0.52) | LTA4HCA1CA2CA9MEN1 | |
| SCHEMBL5537810 | 0.83 | SMN1; SMN2 (0.47) | LTA4HCA4CA1CA2CA7 | |
| SCHEMBL76698 | 0.83 | LTA4H (0.50) | LTA4HCA4CA1CA2CA9 | |
| SCHEMBL28770243 | 0.81 | LTA4H (0.48) | LTA4HCA4CA1CA2CA9 | |
| SCHEMBL5534936 | 0.80 | CA12 (0.50) | CA4CA12CA1CA2CA7 | |
| SCHEMBL1532077 | 0.80 | MAPT (0.42) | LTA4HCA1CA2CA9CA14 | |
| SCHEMBL1220986 | 0.80 | LTA4H (0.54) | LTA4HMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL1532042 | 0.80 | ALDH1A1 (0.39) | LTA4HALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980387-B | Serine/threonine kinase inhibitor | 阵列生物制药公司 | 2019-04-19 | — | — | CN | claimed |
| EP-3089980-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2018-01-31 | — | — | EP | claimed |
| US-9670208-B2 | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2017-06-06 | — | — | US | claimed |
| EP-3089980-A1 | SERINE/THREONINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2016-11-09 | — | — | EP | claimed |
| US-20160304519-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-10-20 | — | — | US | claimed |
| CN-105980387-A | Serine/threonine kinase inhibitors | 阵列生物制药公司 | 2016-09-28 | — | — | CN | claimed |
| WO-2015103137-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2015-07-09 | — | — | WO | claimed |
| EP-1976509-B1 | PPAR MODULATORS | EVOLVA SA (CH) | 2014-12-17 | — | — | EP | claimed |
| US-20140288110-A1 | PPAR MODULATORS | EVOLVA SA (CH) | 2014-09-25 | — | — | US | claimed |
| EP-2363127-A1 | PPAR Modulators | Evolva SA (CH) | 2011-09-07 | — | — | EP | claimed |
| US-20110178112-A1 | PPAR Modulators | EVOLVA SA (CH) | 2011-07-21 | — | — | US | claimed |
| EP-1976509-A2 | PPAR MODULATORS | Evolva SA (CH) | 2008-10-08 | — | — | EP | claimed |
| WO-2007138485-A2 | PPAR MODULATORS | EVOLVA SA (US) | 2007-12-06 | — | — | WO | claimed |
| US-20050119332-A1 | Substituted thiophene compounds as modulators of protein tyrosine phosphatases (PTPases) | JEPPESEN LONE (DK) | 2005-06-02 | — | — | US | claimed |
| CN-116159578-A | Iron catalyst for catalyzing oxidative cleavage of lignin model to produce phenol and ester and application thereof | 天津理工大学 | 2023-05-26 | — | — | CN | disclosed |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-02 | — | — | US | disclosed |
| EP-3863642-A1 | COVALENT TARGETING OF E3 LIGASES | The Regents of the University of California (US) | 2021-08-18 | — | — | EP | disclosed |
| US-4578107-A | Herbicidal imidazolidine-2-one derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1986-03-25 | — | — | US | disclosed |
| US-4414210-A | 2-Hydroxyarylethyltriazole fungicides | ROHM AND HAAS COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| US-4413003-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1983-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178112-A1 | PPAR Modulators | PPARD, PPARG, PPARA | LTA4H 2031/4885CA4 4772/4885CA12 4866/4885 |
| US-20140288110-A1 | PPAR MODULATORS | PPARD, PPARG, PPARA | LTA4H 2031/4885CA4 4772/4885CA12 4866/4885 |
| US-20160304519-A1 | SERINE/THREONINE KINASE INHIBITORS | TTBK1, MAP3K1, TNNI3K | LTA4H 3319/4885CA4 2725/4885CA12 1981/4885 |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | RNF114, RNF4, RNF168 | LTA4H 2510/4885CA4 3645/4885CA12 4279/4885 |
| US-20050119332-A1 | Substituted thiophene compounds as modulators of protein tyrosine phosphatases (PTPases) | PTPRCAP, PTPRS, PTPN1 | LTA4H 916/4885CA4 4129/4885CA12 3905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.