Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16673943 | 0.93 | ACHE (0.63) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10812054 | 0.91 | ACHE (0.67) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5246214 | 0.88 | ACHE (0.53) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5546852 | 0.87 | ACHE (0.68) | ACHEEPHX1 | |
| SCHEMBL18902746 | 0.86 | ACHE (0.60) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5246051 | 0.85 | ACHE (0.47) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5249158 | 0.85 | ACHE (0.47) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25220749 | 0.85 | ACHE (0.71) | ACHEEPHX1 | |
| SCHEMBL25228774 | 0.85 | ACHE (0.71) | ACHEEPHX1 | |
| SCHEMBL25277844 | 0.85 | ACHE (0.71) | ACHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190112413-A1 | SILICON-CONTAINING COMPOUND, URETHANE RESIN, STRETCHABLE FILM, AND METHOD FOR FORMING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190112413-A1 | SILICON-CONTAINING COMPOUND, URETHANE RESIN, STRETCHABLE FILM, AND METHOD FOR FORMING THE SAME | PNISR, OR10J3, OXSR1 | ACHE 3406/4885CHRNB2 2427/4885CHRNB4 2254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.