Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.55 |
| ▸ | VIM | P08670 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.38 |
| ▸ | HTR2B | P41595 | 6/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20906849 | 0.97 | CREBBP (0.51) | CREBBPVIMHTR2AHTR2BHTR2C | |
| SCHEMBL20906869 | 0.92 | CREBBP (0.49) | CREBBPVIMHTR2AHTR2BHTR2C | |
| SCHEMBL20906872 | 0.88 | CREBBP (0.42) | CREBBPHTR2AHTR2BHTR2CADRB1 | |
| SCHEMBL13671131 | 0.83 | CREBBP (0.51) | CREBBPVIMMAPTALDH1A1LMNA | |
| SCHEMBL12754797 | 0.82 | CREBBP (0.50) | CREBBPVIMMAPTALDH1A1LMNA | |
| SCHEMBL17424484 | 0.81 | CREBBP (0.49) | CREBBPVIMMAPTALDH1A1LMNA | |
| SCHEMBL20906813 | 0.81 | CREBBP (0.47) | CREBBPVIMHTR2AHTR2BHTR2C | |
| SCHEMBL17424488 | 0.80 | CREBBP (0.47) | CREBBPVIMOPRM1OPRK1MAPT | |
| SCHEMBL21565404 | 0.79 | CREBBP (0.50) | CREBBPVIMMAPTALDH1A1BMP1 | |
| SCHEMBL20906817 | 0.79 | CREBBP (0.45) | CREBBPVIMCTSDALDH1A1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10458995-B2 | Combinatorial synthesis and biomarker development | TEN30 BIOSCIENCES, INC. | 2019-10-29 | — | — | US | disclosed |
| US-20190113521-A1 | COMBINATORIAL SYNTHESIS AND BIOMARKER DEVELOPMENT | TEN30 BIOSCIENCES, INC. | 2019-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190113521-A1 | COMBINATORIAL SYNTHESIS AND BIOMARKER DEVELOPMENT | APP, PSEN2, PSEN1 | CREBBP 167/4885VIM 2118/4885HTR2A 3624/4885 |
| US-10458995-B2 | Combinatorial synthesis and biomarker development | APP, PSEN2, PSEN1 | CREBBP 165/4885VIM 2070/4885HTR2A 3620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.