Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2155052 | 0.82 | ADRB1 (0.66) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL5274705 | 0.81 | MAPT (0.49) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL2246615 | 0.81 | MAPT (0.49) | MAPTALDH1A1NPC1TP53RAB9A | |
| Hydrochloric Acid SCHEMBL27331131 | 0.81 | ADRB1 (0.64) | MAPTALDH1A1NPC1TP53RAB9A | |
| Hydrochloric Acid SCHEMBL4324884 | 0.81 | ADRB1 (0.64) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL4721119 | 0.79 | ADRB1 (0.53) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL20907490 | 0.77 | MEN1 (0.50) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL5238114 | 0.77 | ADRB1 (0.58) | MAPTALDH1A1NPC1TP53RAB9A | |
| Hydrochloric Acid SCHEMBL2155829 | 0.75 | ADRB1 (0.57) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL23732273 | 0.75 | CHRNB2 (0.66) | MAPTALDH1A1NPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019073251-A1 | LYSYL OXIDASE INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2019-04-18 | — | — | WO | disclosed |