Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20899815 | 0.87 | DPP4 (0.39) | HSP90AA1SLC6A3NPSR1TSHRLMNA | |
| SCHEMBL20899715 | 0.87 | DPP4 (0.39) | HSP90AA1SLC6A3NPSR1TSHRLMNA | |
| SCHEMBL28407779 | 0.84 | TSHR (0.37) | HSP90AA1SLC6A3NPSR1TSHRPRCP | |
| SCHEMBL28407777 | 0.84 | TSHR (0.37) | HSP90AA1SLC6A3NPSR1TSHRPRCP | |
| SCHEMBL21112408 | 0.84 | TSHR (0.38) | HSP90AA1SLC6A3NPSR1TSHRLMNA | |
| SCHEMBL20899810 | 0.84 | TSHR (0.38) | HSP90AA1SLC6A3NPSR1TSHRLMNA | |
| SCHEMBL21112802 | 0.81 | BTK (0.39) | KMT2ADRD2HPGDKDM4EALDH1A1 | |
| SCHEMBL29640289 | 0.81 | BTK (0.39) | KMT2ADRD2HPGDKDM4EALDH1A1 | |
| SCHEMBL20907825 | 0.81 | BTK (0.39) | KMT2ADRD2HPGDKDM4EALDH1A1 | |
| SCHEMBL20899811 | 0.76 | LMNA (0.36) | HSP90AA1SLC6A3NPSR1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019075291-A1 | 1-BENZYL-2-IMINO-4-PHENYL-5-OXOIMIDAZOLIDINE DERIVATIVES AS HIV PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2019-04-18 | — | — | WO | disclosed |