Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407777 | 1.00 | TSHR (0.37) | TSHRDPP4DPP7LMNASLC6A3 | |
| SCHEMBL20899815 | 0.85 | DPP4 (0.39) | TSHRDPP4DPP7LMNASLC6A3 | |
| SCHEMBL20899715 | 0.85 | DPP4 (0.39) | TSHRDPP4DPP7LMNASLC6A3 | |
| SCHEMBL20908006 | 0.84 | HSP90AA1 (0.39) | TSHRDPP4DPP7LMNASLC6A3 | |
| SCHEMBL20899810 | 0.82 | TSHR (0.38) | TSHRDPP4DPP7LMNASLC6A3 | |
| SCHEMBL21112408 | 0.82 | TSHR (0.38) | TSHRDPP4DPP7LMNASLC6A3 | |
| SCHEMBL20899811 | 0.80 | LMNA (0.36) | TSHRDPP4DPP7LMNASLC6A3 | |
| SCHEMBL21112802 | 0.78 | BTK (0.39) | GAAALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL20907825 | 0.78 | BTK (0.39) | GAAALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL29640289 | 0.78 | BTK (0.39) | GAAALDH1A1HPGDKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212832-B | 1-Benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-111212832-A | 1-benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2020-05-29 | — | — | CN | disclosed |