SCHEMBL20908471

SCHEMBL20908471

O=P1(O)OC[C@H]2O[C@@H](n3cnc4c3ncn3ccnc43)C[C@@H]2OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c3ncn3ccnc43)C[C@@H]2O1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 18/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20908708 0.92 STING1 (0.81) STING1
SCHEMBL24323071 0.91 STING1 (0.71) STING1
SCHEMBL20908500 0.90 STING1 (0.59) STING1
SCHEMBL24258680 0.85 STING1 (0.69) STING1
SCHEMBL24258536 0.85 STING1 (0.69) STING1
SCHEMBL20908440 0.84 STING1 (0.72) STING1
SCHEMBL20908834 0.84 STING1 (0.62) STING1
SCHEMBL24322629 0.83 STING1 (0.49) STING1
SCHEMBL20908445 0.83 STING1 (0.72) STING1
SCHEMBL20908441 0.83 STING1 (0.74) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019074887-A1 CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 2019-04-18 — — WO disclosed
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