Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 11/20 | 0.59 |
| ▸ | PDE4A | P27815 | 5/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20908440 | 0.93 | STING1 (0.72) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL20908833 | 0.93 | STING1 (0.67) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20908445 | 0.93 | STING1 (0.72) | STING1 | |
| SCHEMBL20908471 | 0.90 | STING1 (0.65) | STING1 | |
| SCHEMBL24323009 | 0.86 | STING1 (0.58) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20908476 | 0.85 | STING1 (0.82) | STING1PDE3BPDE3A | |
| SCHEMBL20908441 | 0.85 | STING1 (0.74) | STING1 | |
| SCHEMBL20908716 | 0.85 | STING1 (0.74) | STING1 | |
| SCHEMBL20547873 | 0.83 | STING1 (0.77) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL23476915 | 0.83 | STING1 (0.86) | STING1LMNAGMNNRAPGEF3BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074887-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-18 | — | — | WO | disclosed |