Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258664 | 0.85 | LMNA (0.42) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL21263942 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL22300011 | 0.81 | LMNA (0.48) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL17001491 | 0.79 | POLB (0.54) | ALDH1A1KDM4EPOLB | |
| SCHEMBL2775081 | 0.79 | POLB (0.54) | ALDH1A1KDM4EPOLB | |
| SCHEMBL23352540 | 0.79 | POLB (0.54) | ALDH1A1KDM4EPOLB | |
| SCHEMBL18769456 | 0.79 | POLB (0.54) | ALDH1A1KDM4EPOLB | |
| SCHEMBL3893075 | 0.79 | POLB (0.54) | ALDH1A1KDM4EPOLB | |
| SCHEMBL3949956 | 0.78 | LMNA (0.67) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL17703982 | 0.78 | LMNA (0.67) | ALDH1A1LMNATP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074887-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-18 | — | — | WO | disclosed |