Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258630 | 0.76 | CYP1A2 (0.46) | CYP1A2ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL24444132 | 0.76 | CYP1A2 (0.46) | CYP1A2ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL24681153 | 0.74 | ADORA2A (0.38) | CYP1A2ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL25688724 | 0.70 | SLC29A1 (0.49) | LMNA | |
| SCHEMBL24258540 | 0.70 | ALDH1A1 (0.39) | CYP1A2ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL21264012 | 0.70 | SLC29A1 (0.46) | CYP1A2LMNAPOLA1 | |
| SCHEMBL24258662 | 0.70 | SLC29A1 (0.40) | LMNA | |
| SCHEMBL10015776 | 0.69 | PNP (0.48) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL26152433 | 0.69 | PNP (0.48) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL21263864 | 0.67 | SLC29A1 (0.56) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074887-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-18 | — | — | WO | disclosed |