Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20908767 | 0.84 | ALDH1A1 (0.59) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL24258568 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL4528206 | 0.76 | PNP (0.54) | LMNA | |
| SCHEMBL21362231 | 0.73 | CDK1 (0.36) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL10015783 | 0.72 | ALDH1A1 (0.68) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL2294538 | 0.72 | ALDH1A1 (0.68) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL10015776 | 0.72 | PNP (0.48) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL20908775 | 0.72 | ALDH1A1 (0.42) | ALDH1A1LMNA | |
| SCHEMBL24258539 | 0.72 | SLC29A1 (0.42) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL23619277 | 0.70 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752516-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-02-23 | — | — | EP | disclosed |