Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090895 | 0.86 | LPAR1 (0.49) | LPAR1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10252993 | 0.86 | POLB (0.58) | LPAR1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL514342 | 0.84 | POLB (0.60) | ALDH1A1POLBGAALMNAHPGD | |
| SCHEMBL7223111 | 0.83 | ALDH1A1 (0.59) | LPAR1ALDH1A1POLBGAATHRB | |
| SCHEMBL6448297 | 0.82 | ALDH1A1 (0.55) | LPAR1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5497672 | 0.82 | LPAR1 (0.52) | LPAR1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11659356 | 0.82 | HPGD (0.64) | ALDH1A1POLBLMNAHPGDALOX15 | |
| SCHEMBL8207529 | 0.82 | PLAU (0.47) | LPAR1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10490015 | 0.82 | LPAR2 (0.41) | LPAR1ALDH1A1GAALMNAHPGD | |
| SCHEMBL5032627 | 0.81 | GRIN2D (0.60) | LPAR1ALDH1A1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102349540-B | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG | 2015-07-22 | — | — | CN | disclosed |
| CN-101077072-B | Pesticide composition | NOVARTIS AG | 2012-08-08 | — | — | CN | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| CN-102349540-A | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG | 2012-02-15 | — | — | CN | disclosed |
| EP-1506172-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-03-30 | — | — | EP | disclosed |
| CN-101836656-A | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG | 2010-09-22 | — | — | CN | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| CN-100399898-C | Pesticide composition | NOVARTS AG (CH) | 2008-07-09 | — | — | CN | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| CN-101147486-A | Oxadiazine pesticidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-26 | — | — | CN | disclosed |
| CN-101099467-A | Pesticidal compositions | SYNGENTA CROP PROT INC (CH) | 2008-01-09 | — | — | CN | disclosed |
| CN-101077072-A | Pesticide composition | NOVARTIS AG (CH) | 2007-11-28 | — | — | CN | disclosed |
| CN-1739351-A | Pesticide composition | NOVARTS AG (CH) | 2006-03-01 | — | — | CN | disclosed |
| CN-1401234-A | Pesticide composition | NOVARTIS AG (CH) | 2003-03-12 | — | — | CN | disclosed |
| CN-1092488-C | Pesticide composition | NOVARTIS AG (CH) | 2002-10-16 | — | — | CN | disclosed |
| US-6420381-B1 | ACYL-COA: CHOLESTEROL ACYL TRANSFERASE (ACAT) INHIBITORY ACTIVITY, AND IS USEFUL AS AN AGENT FOR TREATMENT OF HYPERLIPIDEMIA AND ATHEROSCLEROSIS. | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1104763-A1 | NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-06-06 | — | — | EP | disclosed |
| CN-1220578-A | Pesticide composition | NOVARTIS AG (CH) | 1999-06-23 | — | — | CN | disclosed |
| CN-1161690-A | Substituted pyridines, their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-10-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | LPAR1 916/4885ALDH1A1 412/4885GRIN2D 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.