Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.71 |
| ▸ | FAAH | O00519 | 5/20 | 0.68 |
| ▸ | NAAA | Q02083 | 1/20 | 0.67 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.61 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30970182 | 1.00 | CASP2 (0.71) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL15369060 | 1.00 | CASP2 (0.71) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL20714965 | 1.00 | CASP2 (0.71) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL12250891 | 1.00 | CASP2 (0.71) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL15003766 | 1.00 | CASP2 (0.71) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL22221624 | 0.98 | CASP2 (0.69) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL24155324 | 0.96 | CASP2 (0.71) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL18627446 | 0.96 | CASP2 (0.71) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL30970230 | 0.96 | FAAH (0.68) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL23344139 | 0.96 | FAAH (0.68) | CASP2FAAHNAAADNM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019073482-A1 | INTRAVENOUS INFUSION DOSAGE FORM FOR PEMETREXED | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2019-04-18 | — | — | WO | disclosed |