Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23011091 | 0.85 | DPP8 (0.43) | WEE1NAMPTFPR1FPR2DPP7 | |
| SCHEMBL450030 | 0.85 | HSD17B3 (0.44) | WEE1NR1H2NAMPTHSD17B3HDAC8 | |
| SCHEMBL20875568 | 0.85 | NR1H2 (0.42) | WEE1NR1H2NAMPTHSD17B3HDAC8 | |
| SCHEMBL20883875 | 0.82 | BCHE (0.43) | WEE1FPR1FPR2HPGD | |
| SCHEMBL20889837 | 0.82 | WEE1 (0.40) | WEE1FPR1FPR2KDM4EALDH1A1 | |
| SCHEMBL7655450 | 0.80 | ESR1 (0.42) | WEE1NR1H2NAMPTHSD17B3HDAC8 | |
| SCHEMBL29507872 | 0.78 | NR1H2 (0.64) | WEE1NR1H2NAMPTKDM4EALDH1A1 | |
| SCHEMBL446262 | 0.78 | NR1H2 (0.64) | WEE1NR1H2NAMPTKDM4EALDH1A1 | |
| SCHEMBL1952271 | 0.75 | LMNA (0.33) | NR1H2HSD17B3KDM4EALDH1A1HPGD | |
| SCHEMBL29506598 | 0.73 | ADRA2C (0.39) | WEE1NR1H2HSD17B3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |