Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998515 | 0.82 | UHRF1 (0.45) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL13806007 | 0.81 | UHRF1 (0.43) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL21201306 | 0.79 | ALDH1A1 (0.39) | CCR5KDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL22313139 | 0.79 | NUDT1 (0.31) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL26715466 | 0.79 | UHRF1 (0.42) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL29608524 | 0.78 | UHRF1 (0.48) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL129055 | 0.78 | UHRF1 (0.48) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL29508711 | 0.77 | UHRF1 (0.52) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL179285 | 0.77 | UHRF1 (0.52) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL20890556 | 0.77 | MEN1 (0.34) | KMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |