SCHEMBL20910232

SCHEMBL20910232

C[SiH](C)c1ccc(/C=C/c2ccc(N(c3ccc(/C=C/c4ccc([Si](C)(C)C)cc4)cc3)c3ccc(/C=C/c4ccc([Si](C)(C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
CASP1 P29466 2/20 0.36
HBB P68871 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
ALOX15 P16050 1/20 0.36
RELA Q04206 1/20 0.34
APP P05067 7/20 0.33
ALDH1A1 P00352 2/20 0.31
HTT P42858 2/20 0.31
GAA P10253 1/20 0.31
BRCA1 P38398 1/20 0.31
CASP7 P55210 1/20 0.31
PTGS1 P23219 1/20 0.31
LMNA P02545 1/20 0.31
ALPG P10696 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9604058 0.88 MAPT (0.44) MAPTMEN1KMT2ASMN1; SMN2CASP1
SCHEMBL12128520 0.82 MAPT (0.40) MAPTMEN1KMT2ASMN1; SMN2CASP1
SCHEMBL12128483 0.82 MAPT (0.40) MAPTMEN1KMT2ASMN1; SMN2CASP1
SCHEMBL14461262 0.78 ALOX5 (0.44) MAPTMEN1KMT2ASMN1; SMN2CASP1
SCHEMBL15298706 0.78 MAPT (0.37) MAPTMEN1KMT2ASMN1; SMN2CASP1
SCHEMBL3409938 0.78 NR1H2 (0.38)
SCHEMBL16501158 0.78
SCHEMBL19735992 0.77 MAPT (0.36) MAPTMEN1KMT2ASMN1; SMN2CASP1
SCHEMBL30307012 0.77 CYP1A2 (0.51) MAPTSMN1; SMN2NPC1RAB9ARELA
SCHEMBL13636797 0.77 CYP1A2 (0.42) MAPTMEN1KMT2ASMN1; SMN2CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10686132-B2 Formulations comprising organic at least two semiconducting compounds and at least two solvents MERCK PATENT GMBH (DE) 2020-06-16 US disclosed
US-20190115536-A1 FORMULATIONS COMPRISING ORGANIC AT LEAST TWO SEMICONDUCTING COMPOUNDS AND AT LEAST TWO SOLVENTS MERCK PATENT GMBH (DE) 2019-04-18 US disclosed