SCHEMBL3409938

SCHEMBL3409938

C[SiH](C)c1ccc([Si](C)(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11416836 0.83 HPGD (0.46) NR1H2NR1H3HPGD
SCHEMBL15241137 0.82 ESR1 (0.37) NR1H2NR1H3
SCHEMBL19785202 0.82 SCN5A (0.31)
SCHEMBL2452756 0.80 NR1H2 (0.39) NR1H2NR1H3HPGD
SCHEMBL18560096 0.79
SCHEMBL586534 0.78 NR1H2 (0.50) NR1H2NR1H3HPGD
SCHEMBL2438805 0.78
SCHEMBL148576 0.78
SCHEMBL20910232 0.78 MAPT (0.36)
SCHEMBL23700583 0.77 HPGD (0.41) NR1H2NR1H3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852230-A Preparation method of polysubstituted hydrosilane compound 中国科学院兰州化学物理研究所 2024-10-29 CN disclosed
CN-114874244-B Preparation method of aryl borate or alkyl borate compound 中国科学院兰州化学物理研究所 2023-12-01 CN disclosed
US-11820912-B2 Fluoropolyether group-containing polymer-modified organic silicon compound, surface treatment agent, and article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-21 US disclosed
EP-4245819-A1 COATING AGENT COMPOSITION, SURFACE TREATMENT AGENT COMPRISING SAID COMPOSITION, AND ARTICLE SURFACE-TREATED WITH SAID SURFACE TREATMENT AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-20 EP disclosed
US-11560494-B2 Coating composition, surface treatment agent containing said composition, and article which is surface-treated with said surface treatment agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-24 US disclosed
CN-114874244-A Preparation method of arylboronic acid ester or alkyl boronate compound 中国科学院兰州化学物理研究所 2022-08-09 CN disclosed
US-11352378-B2 Lipophilic group-containing organosilane compound, surface treatment agent and article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-06-07 US disclosed
US-11069557-B2 Method for producing thin wafer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-07-20 US disclosed
US-20210171799-A1 FLUOROPOLYETHER GROUP-CONTAINING POLYMER-MODIFIED ORGANIC SILICON COMPOUND, SURFACE TREATMENT AGENT, AND ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-06-10 US disclosed
US-20210062039-A1 COATING COMPOSITION, SURFACE TREATMENT AGENT CONTAINING SAID COMPOSITION, AND ARTICLE WHICH IS SURFACE-TREATED WITH SAID SURFACE TREATMENT AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-03-04 US disclosed
US-20160033865-A1 SILICONE STRUCTURE-BEARING POLYMER, NEGATIVE RESIST COMPOSITION, PHOTO-CURABLE DRY FILM, PATTERNING PROCESS, AND ELECTRIC/ELECTRONIC PART-PROTECTING FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-02-04 US disclosed
US-20150293447-A1 SILICONE STRUCTURE-BEARING POLYMER, RESIN COMPOSITION, AND PHOTO-CURABLE DRY FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-10-15 US disclosed
US-9091919-B2 Silicone structure-bearing polymer, resin composition, and photo-curable dry film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-07-28 US disclosed
US-20130196114-A1 SILICONE STRUCTURE-BEARING POLYMER, RESIN COMPOSITION, AND PHOTO-CURABLE DRY FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-08-01 US disclosed
US-8476379-B2 Silphenylene skeleton-containing silicone type polymer and method for manufacturing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-07-02 US disclosed
US-20120094222-A1 PHOTOCURABLE RESIN COMPOSITION, DRY FILM THEREOF, PATTERN FORMING METHOD, AND ELECTRICAL/ELECTRONIC PART PROTECTIVE FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-04-19 US disclosed
US-7700697-B2 Cured product has high degree of hardness, radiation transparent, noncracking, heat resistant; encapsulation agents for optical devices, electronics such as semiconductors; dielectric coating; mixture of unsaturated cyclic silane compound and unsaturated silanediol SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-04-20 US disclosed
US-20080281117-A1 POLYCYCLIC HYDROCARBON GROUP-CONTAINING ORGANOSILICON COMPOUND HAVING HYDROGEN ATOMS BONDED TO SILICON ATOMS, AND METHOD OF PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-11-13 US disclosed
US-20080281056-A1 Cured product has high degree of hardness, radiation transparent, noncracking, heat resistant; encapsulation agents for optical devices, electronics such as semiconductors; dielectric coating; mixture of unsaturated cyclic silane compound and unsaturated silanediol SHIN -ETSU CHEMICAL CO., LTD. (JP) 2008-11-13 US disclosed
US-7323250-B2 Curable silicone resin composition, sealing material for optical semiconductor, and optical semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281117-A1 POLYCYCLIC HYDROCARBON GROUP-CONTAINING ORGANOSILICON COMPOUND HAVING HYDROGEN ATOMS BONDED TO SILICON ATOMS, AND METHOD OF PRODUCING SAME PIEZO1, TRPA1, HEATR6 NR1H2 1033/4885NR1H3 991/4885HPGD 1915/4885
US-20160033865-A1 SILICONE STRUCTURE-BEARING POLYMER, NEGATIVE RESIST COMPOSITION, PHOTO-CURABLE DRY FILM, PATTERNING PROCESS, AND ELECTRIC/ELECTRONIC PART-PROTECTING FILM SMC4, SMC3, PUF60 NR1H2 4466/4885NR1H3 4271/4885HPGD 4539/4885
US-11352378-B2 Lipophilic group-containing organosilane compound, surface treatment agent and article NR1H3, NR1H2, NR1I2 NR1H2 2/4885NR1H3 1/4885HPGD 4335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.