SCHEMBL2091108

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2091112	1.00	PIM1 (0.44)	PIM1PIM2CHEK1CHRM2CHRM1
	SCHEMBL2090543	0.84	GRIK1 (0.34)	PIM1PIM2
	SCHEMBL2095720	0.83	PIM1 (0.47)	PIM1PIM2CHEK1CHRM2CHRM1
	SCHEMBL2095719	0.83	PIM1 (0.47)	PIM1PIM2CHEK1CHRM2CHRM1
	SCHEMBL5548259	0.83	PIM1 (0.42)	PIM1PIM2CHEK1CHRM2CHRM1
	SCHEMBL5548260	0.83	PIM1 (0.42)	PIM1PIM2CHEK1CHRM2CHRM1
	SCHEMBL2091116	0.82	PIM1 (0.46)	PIM1PIM2CHEK1CHRM2CHRM1
	SCHEMBL2091007	0.81	GRIK1 (0.48)	PIM1PIM2MAOB
	SCHEMBL2091009	0.81	GRIK1 (0.48)	PIM1PIM2MAOB
	SCHEMBL2092400	0.80	FBP1 (0.53)	MAOAMAOBNFE2L2FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.